Figure 5: Microscopic examination of a carotid artery stenosis model in hypercholesterolemic minipigs. (a) The stenosed segments with signs of previous thrombosis. (b), (c) and (d). The plaque proximal to the stenosis. Panels a and b are trichrome-elastin stains (collagen blue, smooth muscle cells red, elastin black). (c) Smooth muscle cell actin stain with smooth muscle cells in the fibrous cap covering the necrotic core (asterisk). (d) Macrophage stain with macrophages at the necrotic core border. The scale bar counts for all panels