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   Journal of Cardiovascular Disease Research
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Year : 2011  |  Volume : 2  |  Issue : 3  |  Page : 153-155

Night-time exogenous melatonin administration may be a beneficial treatment for sleeping disorders in beta blocker patients

Department of Internal Medicine, S. Johannes Hospital, Germany

Correspondence Address:
Auda Fares
Department of Internal Medicine, Albert-Schlangen Str. 36 50181, Bedburg
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PMID: 22022142

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Sleep disorders are the common side effects of beta blockers. Beta blockers have been shown to reduce the production of melatonin via specific inhibition of adrenergic beta1-receptors. Exogenous melatonin, taken in the evening as a supplement, could reduce the central nervous system (CNS) side effects (sleep disorder) associated with beta-adrenergic receptor blockers as well as the potential risk associated with reduction of the melatonin synthesis.

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