| INVITED REVIEW |
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| Year : 2010 | Volume
: 1
| Issue : 2 | Page : 59-63 |
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Novel mechanisms of endothelial dysfunction in diabetes
Guang Yang1, Rudolf Lucas2, Ruth Caldwell3, Lin Yao3, Maritza J Romero3, Robert W Caldwell3
1 Vascular Biology Center, Medical College of Georgia, Augusta, GA, USA
2 Vascular Biology Center, Medical College of Georgia, Augusta, GA; Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA, USA
3 Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA, USA
Correspondence Address:
Rudolf Lucas
Vascular Biology Center & Department of Pharmacology and Toxicology, Augusta, GA
USA
DOI: 10.4103/0975-3583.64432
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Diabetes mellitus is a major risk factor for cardiovascular morbidity and mortality. This condition increases the risk of developing coronary, cerebrovascular, and peripheral arterial disease fourfold. Endothelial dysfunction is a major contributor to the pathogenesis of vascular disease in diabetes mellitus patients and has recently received increased attention. In this review article, some recent developments that could improve the knowledge of diabetes-induced endothelial dysfunction are discussed. |
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