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INVITED REVIEW
Year : 2010  |  Volume : 1  |  Issue : 3  |  Page : 99-103

High density lipoproteins-based therapies for cardiovascular disease


Department of Physiology and Biophysics, Boston University School of Medicine, 700 Albany St. W302, Boston, MA 02118, USA

Correspondence Address:
Xuan Gao
Department of Physiology and Biophysics, Boston University School of Medicine, 700 Albany St. W302, Boston, MA 02118
USA
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DOI: 10.4103/0975-3583.70898

PMID: 21187875

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Atherosclerosis is the leading cause of death in developed countries. High density lipoproteins (HDL) cholesterol level correlates inversely with the risk of cardiovascular diseases. Thus, HDL has obtained lots of interest for drug development. In this review, we summarized the mechanisms for the antiatherogenic function of HDL, current HDL-based drugs in clinical use and the future direction for HDL-based therapy development.


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